2. Signaling Pathways
  3. Immunology/Inflammation
  4. NOD-like Receptor (NLR)
  5. NOD-like Receptor (NLR) Modulator

NOD-like Receptor (NLR) Modulator

NOD-like Receptor (NLR) Isoform Comparison

NOD-like Receptor (NLR) Modulators (5):

Cat. No. Product Name Effect Purity
  • HY-160757
    NLRP3 modulator 7
    		Modulator
    NLRP3 modulator 7 (Compound 17B) is a NLRP3 inflammasome regulator. NLRP3 modulator 7 has inhibitory activity against IL-1b, and its IC50 is less than 500 nM.
  • HY-156647
    Usnoflast
    		Modulator 98.59%
    Usnoflast is the selective, orally active inhibitor for NLRP3 that blocks the release of IL-1β, and exhibits anti-inflammatory activity.
  • HY-W010253
    Benzylurea
    		Modulator 99.94%
    Benzylurea is an anti-inflammatory agent. Benzylurea inhibits LPS (HY-D1056)-induced upregulation of MTCH2 expression and regulates pathways associated with mitochondrial function, inflammation and cell survival. Benzylurea alleviates LPS-induced proliferation inhibition and apoptosis of periodontal ligament fibroblasts, as well as the release of proinflammatory cytokines. Benzylurea can be used in studies related to periodontitis.
  • HY-103715
    NLRP3 modulator 1
    		Modulator
    NLRP3 modulator 1 is the potent modulator of NLRP3. NLRP3 modulator 1 agonizes or partially agonizes NLRP3 that are useful for researching a condition, disease or disorder in which a decrease in LRP3 activity contributes to the pathology (extracted from patent WO2017184746A1, compound 107).
  • HY-CE00479
    (6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA
    		Modulator
    (6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA ((6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-coenzyme A) is a NLRX1 modulator. (6Z,9Z,12Z,15Z,18Z,21Z)-Tetracosahexaenoyl-CoA is promising for research of immune and metabolic related diseases.